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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCFC1
All Species:
18.48
Human Site:
Y1848
Identified Species:
36.97
UniProt:
P51610
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51610
NP_005325.2
2035
208732
Y1848
D
L
G
T
V
P
D
Y
N
Q
L
K
K
Q
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088011
1702
173511
P1518
G
P
R
Q
Q
L
P
P
R
Q
L
L
Q
S
A
Dog
Lupus familis
XP_867443
2039
208943
Y1852
D
S
G
T
V
P
D
Y
N
Q
L
K
K
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61191
2045
210519
Y1858
D
S
G
T
V
P
D
Y
N
Q
L
K
K
Q
E
Rat
Rattus norvegicus
Q5RKG2
723
79130
T539
V
G
I
F
K
N
N
T
A
L
V
S
Q
F
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509058
2033
207643
Y1847
D
S
G
T
I
P
D
Y
N
Q
L
K
K
Q
E
Chicken
Gallus gallus
XP_001234928
787
86020
S603
V
G
I
F
K
N
S
S
A
V
V
S
Q
F
Y
Frog
Xenopus laevis
NP_001087989
2101
219049
Y1915
D
S
V
V
L
P
D
Y
S
Q
L
K
K
Q
E
Zebra Danio
Brachydanio rerio
Q7ZUV7
1173
122182
S989
Q
A
H
H
P
V
G
S
S
K
T
S
S
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4C8
1500
160166
R1316
L
E
P
G
T
A
Y
R
F
R
L
S
A
I
N
Honey Bee
Apis mellifera
XP_624189
1550
166762
R1366
Q
G
T
I
Y
K
L
R
I
A
A
V
N
S
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791039
1216
126587
N1032
Q
L
A
K
K
D
V
N
Q
W
Y
D
V
G
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
82.3
93.8
N.A.
93.7
24.2
N.A.
82.4
26.3
68.8
20.4
N.A.
33
34.2
N.A.
37
Protein Similarity:
100
N.A.
82.5
95
N.A.
95.5
30
N.A.
86
32.2
76.6
33.1
N.A.
47.5
50.2
N.A.
46.5
P-Site Identity:
100
N.A.
13.3
93.3
N.A.
93.3
0
N.A.
86.6
0
66.6
0
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
N.A.
20
93.3
N.A.
93.3
20
N.A.
93.3
13.3
80
13.3
N.A.
13.3
0
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
9
0
0
17
9
9
0
9
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
42
0
0
0
0
9
42
0
0
0
0
9
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
42
% E
% Phe:
0
0
0
17
0
0
0
0
9
0
0
0
0
17
0
% F
% Gly:
9
25
34
9
0
0
9
0
0
0
0
0
0
17
0
% G
% His:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
17
9
9
0
0
0
9
0
0
0
0
9
9
% I
% Lys:
0
0
0
9
25
9
0
0
0
9
0
42
42
0
0
% K
% Leu:
9
17
0
0
9
9
9
0
0
9
59
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
17
9
9
34
0
0
0
9
0
9
% N
% Pro:
0
9
9
0
9
42
9
9
0
0
0
0
0
0
0
% P
% Gln:
25
0
0
9
9
0
0
0
9
50
0
0
25
42
0
% Q
% Arg:
0
0
9
0
0
0
0
17
9
9
0
0
0
0
0
% R
% Ser:
0
34
0
0
0
0
9
17
17
0
0
34
9
17
0
% S
% Thr:
0
0
9
34
9
0
0
9
0
0
9
0
0
0
0
% T
% Val:
17
0
9
9
25
9
9
0
0
9
17
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
9
42
0
0
9
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _